Andrieu, "Field-gradient-induced birefringence in dilute solutions of furan,
thiophen and selenophen in cyclohexane," Journal of the Chemical Society, Faraday Transactions 2,vol.
[sup.1]H-NMR (300 MHz, DMSO-d6]): [delta] ppm 8.3 (8.8) (doublet, 2H, ArH, J = 6.8 Hz), 8.2 (8.6) (doublet, 2H, ArH, J = 6.8 Hz), 7.9 (7.7) (singlet, [sup.1]H, pyrimidine), 7.8 (5.8) (singlet, 1H, OH, [D.sub.2]O exchangeable), 7.1-7.7 (7.3-8) (multiplet, 3H,
thiophen), anal.
In this work, we report our investigation on the alane-trihalide (Al[X.sub.3], X = F, Cl, and Br) donor-acceptor complexes [X.sub.3]Al-Y[C.sub.4][H.sub.4] (Y = O in furan, Y = NH in pyrrole, and Y = S in
thiophen) compared to the alane [H.sub.3]Al-Y[C.sub.4][H.sub.4] ones.
Keeping in mind the bioactivity of Schiff bases, a novel Schiff base bearing furan and
thiophen rings has been synthesized and evaluated for the in vitro antifungal activity against Fusarium oxysporum f.sp albedinis FAO fungal strains and the anticancer activity toward breast (MDA-MB231) and colorectal (LoVo) human cell lines cancers.
Serafinowska, "The synthesis of 5-alkoxy and 5-amino substituted
thiophenes," Tetrahedron Letters, vol.
Thiophenes are abundant in pharmaceuticals and natural products.