References in periodicals archive ?
Targeting of the inhibitor enzyme Notum may provide a new way to increase the therapeutic window and to promote recovery in societies with the aging population.
Researchers believe that in addition to direct targeting of Notum, lifestyle factors such as diet may also provide means to reduce Notum, and thus improve tissue renewal and repair.
A clue to the solution came from Petersen's previous research that identified the secreted protein Notum as a component of a tissue organizer needed for head regeneration in planarians.